Sep 8

Seafood + dimension C is not arsenic poisoning 不指定

I do not know the history of how long people prawns, whether it is before eating crabs. Only in respect of a clinician's awareness of arsenic poisoning patients to see their common cause with working contact with the misuse of prescriptions, and environmental pollution. Also know that in some regions because of arsenic in drinking water is too high, or high levels of arsenic in coal, resulting in endemic arsenic poisoning. If both prawns and vitamin C can lead to arsenic poisoning case, for going through to eat from eat, take the initiative to adjust the diet of the people, is undoubtedly a heavy blow.

Users to answer the question, I chose to browse relevant information, the results surprised me. Taiwan reports distributed to them for no reason a girl bleeding suddenly died suddenly, "experts" to explain: "The problem was that she ate dinner a lot of shrimp, prawns in itself no problem, but the man at the same time taking vitamin C, the problem lies In here! "Thus while prawns and vitamin C can lead to arsenic poisoning, and acute arsenic poisoning, but deadly! So, friends exclaimed: I just ate 20 shrimp and two oranges, how is Good!

That prawns lead poisoning, there is a large crack down the suspects. Many varieties of shrimp, place of origin are many. Caused by arsenic poisoning shrimp, shrimp first identified as "high arsenic" animals, see a Heaven's a no miscarriage of justice. 2009, Journal of Food Science Papers, Chinese scientists on the Arctic sweet shrimp imports and distribution of heavy metals were studied. The results show that if the whole object only for the detection of shrimp, sweet shrimp samples in the Arctic lead content 0.172mg/kg (national health standard 0.5mg/kg), total mercury 0.032mg/kg (national health standard 0.5mg/kg), Cadmium 0.788mg/kg (national health standard 0.5mg/kg), inorganic arsenic 0.036mg/kg (national health standard 0.5mg/kg), excessive cadmium removal, the other a national standard to control test indicators are satisfactory.

Study found that shrimp's head is a major part of heavy metals, as head of the prawn is not our usual perception of the "head" which is shrimp and water metabolism interactive portal, but also shrimp, liver, pancreas, kidneys and other organs agglomeration area. Even so, the head of the prawn outside the test results in addition to excessive cadmium, lead, mercury, inorganic arsenic also are in line with China's health standards. It can be concluded that shrimp is not a "high-arsenic" animal, its food safety problems and there is no essential difference between other aquatic products; the so-called issue of arsenic in shrimp in vivo, but also with other heavy metal pollution in aquatic product line; aquatic pollution is the case, not because of "Minamata disease", said fish caused mercury poisoning.

Arsenic is an ancient poison, arsenic is generally considered the German Albertus Magnus in 1250 to co-heating realgar and soap obtained; in fact, my home is the ancient alchemy of arsenic in the first discoverer. According to historical records, about AD 317, China's alchemy home with realgar Ge Hong, turpentine, saltpeter refining three substances was arsenic. Based on years of clinical studies, people's knowledge of arsenic poisoning has been considerable understanding.

While prawns and vitamin C can lead to the mechanism of arsenic poisoning is not convincing. First, the toxicity of arsenic and its compounds, to a large extent depend on its water solubility. Toxicology studies have shown that the toxicity of trivalent arsenic than pentavalent ion of arsenic ions. Highly toxic arsenic trioxide ,0.8-2mg / kg may lead to an adult poisoning. The five acute toxicity of arsenic oxide is a highly toxic, rat oral 8mg/kg half of experimental animals caused death; mice induced by oral 55mg/kg half the animals died. From this, pentavalent arsenic lead poisoning, without conversion to trivalent arsenic.

That pentavalent arsenic in the effect of vitamin C into trivalent arsenic, I did not find the relevant literature to support, only to see the 300C. Conditions, five will lose part of the arsenic oxide oxygen, converted to arsenic trioxide. Infer that the statement is as acidic vitamin C, can provide reduction of hydrogen ions and then play a role. If you take into account any intake of food, must first come into contact with the acidic stomach environment, and then worry about vitamin C on the reduction of pentavalent arsenic, is tantamount to asking for trouble.

On Earth is a microcosm of the global environment. Living species on this planet, the body of material more or less reflect the existence of material in the environment, so people did not find arsenic-free products may be. Living species on this planet is gradually adapting to the Earth's ecological products, studies have shown that organisms have to enter the body, low toxicity of arsenic into organic arsenic, and save, metabolic capacity, humans also do so.

Avoid intake of arsenic, can eat shrimp head, but everything can not go to the extreme. Studies have shown that arsenic is the human body must trace elements, extreme lack of people of the health situation will deteriorate. Sheep, miniature pigs and chickens results show that feed containing arsenic in drinking water is low, leading to growth retardation, pregnancy reduction, more spontaneous abortions, higher mortality rate. It was observed that in the long-term hemodialysis patients, the reduction of arsenic content in blood, may be associated with central nervous system disorders, vascular diseases related to high.

Summer heat is about to end, in ushering in autumn when the market is large concentrations of shrimp season, I think you can safely eat shrimp, I have no vitamin C exist, no doubt, people's normal diet, which meal does not contain a considerable dose of vitamin C do? However, prawns and maintenance of C, not arsenic poisoning!
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2011/11/28 14:21
Shrimp, Vitamin C & Arsenic poisoningMarine organisms normally contain arsenic residues ranging from < 1 to more than 100 mg/kg, predominantly as organic arsenic species such as arsenosugars (macroalgae) and arsenobetaine (invertebrates and fish). Bioaccumulation of organic arsenic compounds, after their biogenesis from inorganic forms, occurs in aquatic organisms. Bioconcentration factors in freshwater invertebrates and fish for arsenic compounds are lower than for marine organisms. Biomagnification in aquatic food chains has not been observed. Background arsenic concentrations in freshwater and terrestrial biota are usually less than 1 mg/kg (fresh weight). With the exception of fish, most foods contain less than 0.25 µg/g arsenic. Many species of fish contain between 1 and 10 µg/g. Arsenic levels at or above 100 µg/g have been found in bottom feeders and shellfish. Both lipid- and water-soluble organoarsenic compounds have been found but the water-soluble forms constitute the larger portion of the total arsenic content. The nature of these compounds has been shown to be mainly of the quaternary arsonium type. As was mentioned above, arsenobetaine is believed to be the most predominant species, but recent Canadian results demonstrated a higher level of arsenocholine than arsenobetaine in shrimps.Vitamin C or L-ascorbic acid or L-ascorbate is an essential nutrient for humans and certain other animal species. In living organisms ascorbate acts as an antioxidant by protecting the body against oxidative stress. It is also a cofactor in at least eight enzymatic reactions including several collagen synthesis reactions that, when dysfunctional, cause the most severe symptoms of scurvy. In animals these reactions are especially important in wound-healing and in preventing bleeding from capillaries.Ascorbate (an ion of ascorbic acid) is required for a range of essential metabolic reactions in all animals and plants. It is made internally by almost all organisms although notable mammalian group exceptions are most or all of the order chiroptera (bats), guinea pigs, capybaras, and one of the two major primate suborders, the Anthropoidea (Haplorrhini) (tarsiers, monkeys and apes, including human beings). Ascorbic acid is also not synthesized by some species of birds and fish. All species that do not synthesize ascorbate require it in the diet. Deficiency in this vitamin causes the disease scurvy in humans. It is also widely used as a food additive. Although there is no compelling evidence that vitamin C has antitumor activity in humans, clinical trials are testing the hypothesis that ascorbic acid will enhance the efficacy of arsenic trioxide (As2O3) in myeloma. In vitro, ascorbic acid cytotoxicity depends on its interaction with free transition metal ions in culture media leading to the generation of H2O2 and other reactive oxygen species. To circumvent the extracellular in vitro pro-oxidant effects of ascorbic acid, HL60, U266, and RPMI-8226 cells are loaded with vitamin C by incubation with dehydroascorbic acid. Loading cells in this manner resulted in prominent, dose-dependent protection of As2O3-treated cells as measured by viability, colony formation, and apoptosis assays. Glutathione depletion enhanced cell sensitivity to the cytotoxic effects of As2O3 and vitamin C loading provided protection. Ascorbic acid was found to generate cytotoxic concentrations of H2O2 in culture medium without cells and copper/iron chelators inhibited this reaction. However, ascorbic acid did not generate H2O2 in simple buffer or human plasma. Direct incubation with ascorbic acid  resulted in increased intracellular reactive oxygen species , whereas dehydroascorbic acid incubation decreased it. These results clarify an apparent paradox and indicate that vitamin C loading in HL60, U266, and RPMI-8226 cells ameliorates As2O3 cytotoxicity.
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